High cholesterol : Psyllium is well studied as a lipid-lowering agent with generally modest reductions seen in blood levels of total cholesterol and low-density lipoprotein ("bad cholesterol"). Effects have been observed following eight weeks of regular use. Psyllium does not appear to have significant effects on high-density lipoprotein ("good cholesterol") or triglyceride levels.
Constipation : Psyllium has long been used as a chief ingredient in "bulk laxatives." Generally, an increase in stool weight, an increase in bowel movements per day, and a decrease in total gut transit time has been observed in most studies.
Diarrhea : Psyllium has been studied for the treatment of diarrhea, particularly in patients undergoing tube feeding. It has also been studied in addition to orlistat therapy in hopes of decreasing gastrointestinal effects (diarrhea and oily discharge) of this weight loss agent.
Colon cancer : According to early research, diets that include psyllium may reduce the risk for colon cancer.
Colonoscopy preparation : Patients with new onset constipation or presumed hemorrhoid bleeding frequently require the use of both fiber supplements and diagnostic colonoscopy. Researchers have concluded that in non-constipated patients
Fat excretion in stool :Early research shows that dietary psyllium and chitosan supplementation may help to increase the excretion of fat in the stool.
Gas (flatulence) : Early research suggests that diets high in fiber (such as psyllium) will increase gas production, yet promote gas retention.
Hemorrhoids : Psyllium may reduce the symptoms of hemorrhoids, which can result from constipation.
Hyperglycemia (high blood sugar levels) : Several studies have examined the administration of psyllium with meals or just prior to meals in order to measure effects on blood sugar levels.
Induction of labor/abortion (cervical dilator) : An early study examined whether a preparation made from psyllium could help dilate the cervix when labor or abortion is induced.
Inflammatory bowel disease (Crohn's disease, ulcerative colitis) : There is limited and unclear evidence regarding the use of psyllium in patients with inflammatory bowel disease.
Irritable bowel syndrome : Psyllium preparations have been studied for more than 20 years in the treatment of irritable bowel syndrome symptoms.
Obesity : The reviewed evidence seems to show that psyllium may improve blood sugar and lipid levels, which can be related to obesity in some children.
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